Abstract
THE repopulation of the irradiated adult animal by injected myeloid cells has provided a considerable amount of qualitative and quantitative data on haemopoietic stem cells1. The work reported here was designed to investigate the capacity of cells of various embryonic organs to populate the haemopoietic tissues of the irradiated embryo. The chick embryo is especially suited to such a study, first because haemopoietic cells can be injected intravenously into it, and second because the sex chromosome difference between male (ZZ) and female (ZW) cells provides a marker method for distinguishing the contributions of host and donor to haemopoietic recovery.
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References
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MOORE, M., OWEN, J. Chromosome Marker Studies in the Irradiated Chick Embryo. Nature 215, 1081–1082 (1967). https://doi.org/10.1038/2151081a0
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DOI: https://doi.org/10.1038/2151081a0
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