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Experimental Leptospirosis in Frogs

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Abstract

LEPTOSPIRAL agglutinins or agglutinating factors have been reported in poikilothermic vertebrates collected from the natural environment1–5. Pathogenic leptospires have been isolated from6,7 and experimentally propagated1,8 in lower vertebrates. During follow-up of a human leptospirosis outbreak associated with swimming9,10, leptospires (unidentified) were isolated from the kidney tissue of frogs collected at the place of swimming11. Frogs were inoculated with the leptospiral isolate in an attempt to: (a) produce infection and disease; (b) measure an antibody response; (c) propagate the organism; and (d) develop carriers and shedders.

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References

  1. Van Thiel, P. H., Antonie van Leeuwenhoek, 14, 129 (1948).

    Article  CAS  Google Scholar 

  2. Combiesco, D., Sturdza, N., Radu, I., Sefer, M., and Nicolesco, I., Arch. Roumaines Path. Exp. Microbiol., 18, 361 (1959). (Abstr. in Bull. Hyg., 35, 1006; 1960.)

    Google Scholar 

  3. Van der Hoeden, J., Syenberg, J. E., and Evenchik, Z., Nature, 190, 95 (1961).

    Article  ADS  CAS  Google Scholar 

  4. White, F. H., Amer. J. Vet. Res., 24, 179 (1963).

    Google Scholar 

  5. Andrews, R. D., Reilly, J. R., Ferris, D. H., and Hansen, L. E., Bull. Wildlife Dis. Assoc., 1, 55 (1965).

    Article  Google Scholar 

  6. Ferris, D. H., Rhoades, H. E., Hansen, L. E., Galton, M., and Mansfield, M. E., Cornell Vet., 51, 405 (1961).

    CAS  Google Scholar 

  7. Plesko, I., Janovicova, E., and Lac, J., Zbl. Bakt. I., 192, 482 (1984). (Abstr. in Vet. Bull., 34, 580; 1964.)

    Google Scholar 

  8. Abudulla, P. K., and Karstad, L., Zoonoses Res., 1, 295 (1962).

    Google Scholar 

  9. McCulloch, W. F., Diesch, S. L., Braun, J. L., Top, F. H., and Nelsen, C. E., Eleventh Pacific Science Congress, Tokyo, Japan (1966).

    Google Scholar 

  10. Diesch, S. L., and McCulloch, W. F., Public Health Rep., 81, 299 (1966).

    Article  CAS  Google Scholar 

  11. Diesch, S. L., McCulloch, W. F., Braun, J. L., and Ellinghausen, jun., H. C., Nature, 209, 939 (1966).

    Article  ADS  CAS  Google Scholar 

  12. Ellinghausen, jun., H. C., and McCullough, W. C., Amer. J. Vet. Res., 26, 39 (1965).

    CAS  Google Scholar 

  13. Galton, M. M., Menges, R. W., Shotts, jun., E. B., Nahmias, A. J., and Heath, C. W., Public Health Service Publication No. 951, 1962 (U.S. Department of Health, Education and Welfare).

  14. Ellinghausen, jun., H. C., and McCullough, W. G., Amer. J. Vet. Res., 26, 45 (1965).

    CAS  Google Scholar 

  15. Johnson, R. C., and Rogers, P., J. Bact., 87, 422 (1964).

    CAS  Google Scholar 

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DIESCH, S., MCCULLOCH, W. & BRAUN, J. Experimental Leptospirosis in Frogs. Nature 214, 1139–1140 (1967). https://doi.org/10.1038/2141139a0

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  • DOI: https://doi.org/10.1038/2141139a0

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