Abstract
THE anticoagulant property of heparin is well known, but some of its other effects—such as lipolysis1 and inhibition of platelet aggregation2–6—are less definite. Some compounds of similar structure may possess more lipolytic and anti-aggregating activity and less anticoagulant effect than heparin, and these compounds could conceivably have clinical uses. We have investigated a sulphonic polysaccharide similar to heparin (Fig. 1) in structure, which has a marked fibrinolytic action7,8 and little anticoagulant effect.
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AZNAR, J., LASSO, M. & PLÁ, A. Inhibition of Platelet Aggregation by a Sulphonic Polysaccharide. Nature 213, 1251–1252 (1967). https://doi.org/10.1038/2131251a0
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DOI: https://doi.org/10.1038/2131251a0
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