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Administration of N-Acetyl-D-mannosamine to Mammals

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Abstract

N-ACETYL-D-mannosamine (NAM) is biochemically related to N-acetyl-D-neuraminic acid (NANA), a constituent of both human follicle stimulating hormone and human chorionic gonadotrophin (HCG). The compound itself is devoid of biological activity, but when mixed with HCG it reduces the activity of this hormone in both the uterine weight and ovulation assays1. We therefore considered it to be of interest to study the fate of NAM after the administration of it to mammals.

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References

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Authors and Affiliations

  1. Department of Chemistry, University of Birmingham,

    S. M. AMIR & S. A. BARKER

  2. East Birmingham Hospital, Birmingham, 9

    W. R. BUTT, A. C. CROOKE & A. G. DAVIES

Authors
  1. S. M. AMIR
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  2. S. A. BARKER
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  3. W. R. BUTT
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  4. A. C. CROOKE
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  5. A. G. DAVIES
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AMIR, S., BARKER, S., BUTT, W. et al. Administration of N-Acetyl-D-mannosamine to Mammals. Nature 211, 976–977 (1966). https://doi.org/10.1038/211976a0

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