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Tolerance of Chickens to Thiabendazole

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Abstract

THIABENDAZOLE, a broad-spectrum anthelmintic1,2, is well tolerated by mice, rats and rabbits, with LD50 values exceeding 3.1 g/kg in oral acute toxicity experiments3. Furthermore, rats and dogs tolerated the drug quite well in chronic toxicity experiments3.

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References

  1. Brown, H. D., et al., J. Amer. Chem. Soc., 83, 1764 (1961).

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  2. Cuckler, A. C., J. Parasitol., 47, Suppl., 36 (1961).

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  3. Robinson, H. J., Stoerk, H. C., and Graessle, O. E., Toxicol. App. Pharm., 7, 53 (1965).

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Authors and Affiliations

  1. Merck Institute for Therapeutic Research, Rahway, New Jersey

    D. POLIN, K. KELLEY, E. LEHMAN & W. H. OTT

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  1. D. POLIN
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  2. K. KELLEY
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  3. E. LEHMAN
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  4. W. H. OTT
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POLIN, D., KELLEY, K., LEHMAN, E. et al. Tolerance of Chickens to Thiabendazole. Nature 211, 753–754 (1966). https://doi.org/10.1038/211753b0

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