Abstract
NATURAL crude or purified preparation of adrenocorticotrophic hormone (ACTH) and melanotrophin (MSH) can induce stretching and yawning motions in various species of animals when injected intracisternally. This property is also shared by synthetic polypeptides endowed with MSH and/or ACTH activity1–4.
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References
Ferrari, W., Floris, E., and Paulesu, F., Arch. Intern. Pharmacodyn. Therap., 110, 410 (1957).
Ferrari, W., Nature, 181, 925 (1958).
Ferrari, W., Gessa, G. L., and Vargiu, L., Experientia, 17, 90 (1961).
Ferrari, W., Gessa, G. L., and Vargiu, L., Ann. N.Y. Acad. Sci., 104, 330 (1963).
Walser, A., and Koller, F., Experientia, 19, 320 (1963).
Hall, K. R. L., Nature, 196, 1258 (1962).
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GESSA, G., VARGIU, L. & FERRARI, W. Stretchings and Yawnings induced by Adrenocorticotrophic Hormone. Nature 211, 426–427 (1966). https://doi.org/10.1038/211426a0
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DOI: https://doi.org/10.1038/211426a0
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