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In vivo Transfer of Infectious Drug Resistance

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Abstract

INFECTIOUS drug resistance that can be transferred in vitro from a donor bacterium to a sensitive recipient bacterium can also be transferred in vivo. Transfer has been shown to occur in mice which have had their normal intestinal flora reduced by the preliminary feeding of antibiotics. In such mice the donor and recipient strains become well established and multiply in the intestine1,2.

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References

  1. Kasuya, M., J. Bacteriol., 88, 322 (1964).

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  2. Guinée, P. A. M., Antonie v. Leeuwenhoek, 31, 314 (1965).

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  3. Smith, H. W., and Halls, S., Brit. Med. J., i, 266 (1966).

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Authors and Affiliations

  1. Department of Bacteriology and Immunology, London School of Hygiene and Tropical Medicine, London, W.C.1.

    JOHN R. WALTON

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  1. JOHN R. WALTON
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WALTON, J. In vivo Transfer of Infectious Drug Resistance. Nature 211, 312–313 (1966). https://doi.org/10.1038/211312a0

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