Abstract
IN the central nervous system, the occurrence of mast cells in the pineal1 and neurohypophysis2 appears to be well established. They have been noted in the normal olfactory bulb3. They occur also in the human brain under pathological conditions, for example around infarcts and in the plaques of multiple sclerosis4, as well as around the cerebral vessels of ageing animals5.
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References
Quay, W. B., J. Morph., 98, 471 (1956).
Gray, J. H., J. Anat., 69, 153 (1935).
Torsegno, M. E., Note Riv. Psichiat., April, 215 (1935) cited by Selye, H., The Mast Cells (Butterworths, 1965).
Neumann, J., Virchows Arch. Path. Anat. Physiol., 122, 378 (1890).
Kellsall, M. A., and Lewis, P., Fed. Proc. Fed. Amer. Soc. Exp. Biol., 23, 1107 (1964).
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CAMPBELL, D., KIERNAN, J. Mast Cells in the Central Nervous System. Nature 210, 756–757 (1966). https://doi.org/10.1038/210756b0
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DOI: https://doi.org/10.1038/210756b0
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