Abstract
IT has been found that when wounds are made through the full-thickness of the pinna of the rabbit's ear, and tissue of area 1 cm2 is excised (Fig. 1), the tissue deficit is almost completely made good within 98 days, though a small hole always remains (Fig. 2). This entails the regeneration of relatively mobile dorsal skin, elastic cartilage, connective tissue, nerve fibres and immobile vental skin. Furthermore, the process takes place significantly faster in males than in females. It has been reported elsewhere that if either skin1 or cartilage2 is removed from the rabbit's ear it regenerates, the skin completely and the cartilage partially. The replacement of full-thickness deficits has not, however, been reported.
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JOSEPH, J., DYSON, M. Sex Differences in the Rate of Tissue Regeneration in the Rabbit's Ear. Nature 208, 599–600 (1965). https://doi.org/10.1038/208599a0
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DOI: https://doi.org/10.1038/208599a0
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