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Reciprocal Innervation through Interneuronal Inhibition

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Abstract

IT has recently been shown that L-3,4-dihydroxyphenylalanine (DOPA) depresses the short-latency reflex paths from the flexor reflex afferents (FRA) and releases long-latency reflex paths from these same afferents, which give a prolonged intense activation of ipsilateral flexor and contralateral extensor motoneurones and a concurrent depolarization of Ia primary afferent fibres1,2. In the normal acute spinal cat the long-latency paths are presumably inhibited by the short-latency paths.

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References

  1. Andén, N.-E., Lundberg, A., Rosengren, E., and Vyklický, L., Experientia, 19, 654 (1963).

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  2. Anden, N.-E., Jukes, M. G. M., Lundberg, A., and Vyklický, L., Nature, 202, 1344 (1964).

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  3. Brown, T. Graham, Proc. Roy. Soc., B, 86, 140 (1913).

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JANKOWSKA, E., JUKES, M., LUND, S. et al. Reciprocal Innervation through Interneuronal Inhibition. Nature 206, 198–199 (1965). https://doi.org/10.1038/206198a0

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