Abstract
Bearcroft and Jamieson1 discovered a tumour on the face of a rhesus monkey imported from India to their laboratory in West Africa. In rapid succession, similar tumours appeared in other Asian monkeys housed in the same colony. Andrewes et al.2,3 demonstrated that the tumour was produced by a virus which probably belongs in the pox group. Investigators at the Roswell Park Memorial Institute4–9 classified this tumour as a histiocytoma and demonstrated (by electron microscopy) that the virus was indistinguishable from other viruses of the pox group, although no antigenic relationship to vaccinia or monkey pox virus could be demonstrated. The virus, when inoculated intravenously, produced lesions in the skin and internal organs of Asiatic monkeys, but monkeys imported from Africa appeared to be immune. The susceptibility of human beings to this virus was observed in a laboratory accident in which an injection needle containing Yaba virus suspension accidentally penetrated the skin of an investigator6.
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FELTZ, E. In vitro Culture of Yaba Virus-induced Tumour from Monkeys. Nature 202, 625–626 (1964). https://doi.org/10.1038/202625a0
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DOI: https://doi.org/10.1038/202625a0
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