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Antibody Activity in γ1A-Globulin of Normal Human Serum

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Abstract

ALL antibodies studied so far have been associated with a structurally related group of proteins known as the ‘immunoglobulins’. Included within this group are 7S γ-globulin, γ1M-(or 19S γ-) globulin and γ1A-globulin (synonym β2A-globulin). The latter is an antigenically and physieo-chemically distinct plasma protein which was first detected by immuno-electrophoretic techniques in the sera of patients with multiple myeloma1. Its general properties and antigenic characteristics have been describedby Heremans et al.2 and Franklin and Stanworth3. More recently, Cohen4 has demonstrated that the three immunoglobins include within their structure peptide chains of a similar nature.

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Authors and Affiliations

  1. Department of Experimental Pathology, University of Birmingham,

    D. S. ROWE & M. W. TURNER

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  1. D. S. ROWE
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  2. M. W. TURNER
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ROWE, D., TURNER, M. Antibody Activity in γ1A-Globulin of Normal Human Serum. Nature 202, 103–104 (1964). https://doi.org/10.1038/202103a0

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