Abstract
THE phenol–hypochlorite reaction for ammonia was first described by D. D. Van Slyke and A. Hiller1, and later was modified by M. Borsook2 and J. A. Russell3. Unfortunately this reaction cannot be applied directly to biological fluids, because certain amino-acids, alkylamines and ammonium salts can react to a certain extent. Moreover, Russell's modification, being dependent on small concentrations of molybdenum ion, can be affected by the presence of thiols, thioamides, and in general by any chelating andreducing substances.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Van Slyke, D. D., and Hiller, A., J. Biol. Chem., 102, 499 (1933).
Borsook, M., J. Biol. Chem., 110, 481 (1935).
Russell, J. A., J. Biol. Chem., 156, 457 (1944).
Philpot, J. S. L., and Small, P. A., Biochem. J., 32, 542 (1938).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MUFTIC, M. A New Phenol–Hypochlorite Reaction for Ammonia. Nature 201, 622–623 (1964). https://doi.org/10.1038/201622a0
Issue Date:
DOI: https://doi.org/10.1038/201622a0
- Springer Nature Limited
This article is cited by
-
A new continuous measurement method for gaseous ammonia by counter-current flow tube sampling and indophenol reaction
Journal of Atmospheric Chemistry (2016)
-
Characterization of a recombinant (+)-γ-lactamase from Microbacterium hydrocarbonoxydans which provides evidence that two enantiocomplementary γ-lactamases are in the strain
Applied Microbiology and Biotechnology (2015)
-
Candida amidevorans sp. nov., a new ascomycetous anamorph yeast from soil
Antonie van Leeuwenhoek (1987)
-
Fluoroacetamide resistance mutations in Chlamydomonas reinhardtii
Archives of Microbiology (1987)
-
Induction control of purine catabolism in Schizosaccharomyces pombe
Current Genetics (1985)