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Independence of the Formation of Extracellular Protease on the Amino-acid Level in the Cells of Bacillus megatherium

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Abstract

SYNTHESIS of extracellular protease in micro-organisms is repressed in the presence of free amino-acids in the medium1–3. However, the formation of intracellular enzyme is not influenced by amino-acids. The quantitative relationship between the amount of amino-acids present in the medium, their level in the cells and inhibition of enzyme formation was investigated during short-time incubation.

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Authors and Affiliations

  1. Institute of Microbiology, Czechoslovak Academy of Sciences, Prague

    J. CHALOUPKA, P. KŘEČKOVÁ & L. ŘÍHOVÁ

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  1. J. CHALOUPKA
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  2. P. KŘEČKOVÁ
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  3. L. ŘÍHOVÁ
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CHALOUPKA, J., KŘEČKOVÁ, P. & ŘÍHOVÁ, L. Independence of the Formation of Extracellular Protease on the Amino-acid Level in the Cells of Bacillus megatherium. Nature 200, 885–886 (1963). https://doi.org/10.1038/200885b0

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