Skip to main content
Log in

‘Rebound Effect’ of Ovulation-inhibiting Steroid in Rats

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

WHILE interpreting the results of studies in women and the dual role of ‘Norethynodrel’, Rock describes it as ‘rebound effect’ possibly on the pituitary gland1. It has been shown that syntheses of gonadotrophins are affected by administration of ‘Norethynodrel’2,3. Our recent experiments on this rebound effect phenomenon and the results obtained have brought forth some new thoughts on the role of anterior pituitary gland in gonadotrophic hormone elaboration.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Rock, J., Garcia, C. R., and Pincus, G., Rec. Prog. Horm. Res., 13, 323 (1957).

    CAS  PubMed  Google Scholar 

  2. Drill, V. A., Jap. J. Pharm., 11, 88 (1962).

    Article  CAS  Google Scholar 

  3. Pincus, G., Proc. Symp. 19-Nor Steroids, Chicago, 105 (1957).

  4. Holmes, R. L., and Mandl, A. M., J. Endocrinol., 24, 297 (1962).

    Google Scholar 

  5. Bayliss, W. M., and Starling, E. H., Proc. Roy. Soc., 73, 710 (1904).

    Article  Google Scholar 

  6. Zuckerman, S., Lancet, i, 739 (1954).

  7. Turner, C. D., General Endocrinology (Saunders, 1960).

    Google Scholar 

  8. Nelson, W. O., and Patanelli, D. J., First Intern. Conf. Endocrinol., Copenhagen, 905 (1960).

  9. Burrows, H., Biological Actions of Sex Hormones (Cambridge, 1949).

    Google Scholar 

  10. Ramaswami, L. S., and Lakshman, A. B., Nature, 181, 1210 (1958).

    Article  ADS  CAS  Google Scholar 

  11. Harris, G. W., Physiol. Rev., 28, 139 (1948).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

LAKSHMAN, A., NELSON, W. ‘Rebound Effect’ of Ovulation-inhibiting Steroid in Rats. Nature 199, 608–609 (1963). https://doi.org/10.1038/199608a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/199608a0

  • Springer Nature Limited

This article is cited by

Navigation