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Ring Chromosomes in Human Beings

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Abstract

RING chromosomes have been found in some species, the most intensively studied being maize1 and Drosophila2. They have also been induced by irradiating human cells in vitro3 and are known to occur in human tumours4. We have recently found a ring chromosome in two children, a different chromosome being involved in each case. There are no apparent signs of neoplastic disease in either patient.

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References

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Authors and Affiliations

  1. Department of Medical Genetics, Clinical Investigation and Research Unit, Children's Hospital, Winnipeg

    HSI-CHANG WANG, JOHN MELNYK, LYLE T. MCDONALD & IRENE A. UCHIDA

  2. Department of Paediatrics, University of Manitoba,

    HSI-CHANG WANG, JOHN MELNYK, LYLE T. MCDONALD & IRENE A. UCHIDA

  3. Department of Microscopic Anatomy, Faculty of Medicine, University of Western Ontario, and Children's Psychiatric Research Institute, London, Ontario

    DAVID H. CARR & BENJAMIN GOLDBERG

Authors
  1. HSI-CHANG WANG
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  2. JOHN MELNYK
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  3. LYLE T. MCDONALD
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  4. IRENE A. UCHIDA
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  5. DAVID H. CARR
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  6. BENJAMIN GOLDBERG
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WANG, HC., MELNYK, J., MCDONALD, L. et al. Ring Chromosomes in Human Beings. Nature 195, 733–734 (1962). https://doi.org/10.1038/195733a0

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