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Effect of Enzyme Injections on Mitosis in Regenerating Liver

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Abstract

THE addition of deoxyribonuclease to tissue-culture media affected mitosis in tissue cultures1,2. In mice bearing Ehrlich ascites tumours, injections of the enzyme decreased the incidence of mitoses in the tumour cells and increased the survival-time of the animals3. Similarly, injections of xanthine oxidase and ribonuclease affected the rate of tumour growth and the survival time4–6.

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References

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Author notes

  1. GASTON DE LAMIRANDE: Research Associate of the National Cancer Institute of Canada.

Authors and Affiliations

  1. Montreal Cancer Institute, Research Laboratories, Notre Dame Hospital and University of Montreal, Montreal

    GASTON DE LAMIRANDE

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  1. GASTON DE LAMIRANDE
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DE LAMIRANDE, G. Effect of Enzyme Injections on Mitosis in Regenerating Liver. Nature 191, 400–401 (1961). https://doi.org/10.1038/191400b0

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