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Association of Detectable Antibodies produced by Haemonchus spp. Infections in Cattle, with Serum Globulin Fractions

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Abstract

EARLIER investigations have shown that cattle which exhibit a marked degree of natural resistance to infection with Haemonchus spp. also develop higher complement-fixation titres than susceptible cattle, and that rises in the complement-fixation antibody titres often occurred at the same time as rises in the gamma one fraction of the serum globulin. This resistance has been shown to be heritable1,2. These observations were made under field conditions where extraneous stimuli were likely to produce changes in the globulin fractions, so that the correlation between complement-fixation titres and the γ-1-globulin fraction was not always consistent and definite conclusions were not possible. To clarify this situation, cattle sera known to be positive by the complement-fixation test were fractionated and the fractions identified and tested for antibody content. The following is a brief account of the procedure and results obtained.

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References

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Authors and Affiliations

  1. Federal Veterinary Department, Vom, Nigeria

    J. G. ROSS

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  1. J. G. ROSS
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ROSS, J. Association of Detectable Antibodies produced by Haemonchus spp. Infections in Cattle, with Serum Globulin Fractions. Nature 190, 1019–1020 (1961). https://doi.org/10.1038/1901019b0

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