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Morphogenetic Effects of Lipoic Acid on Amphibian Embryos

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Abstract

WE have recently1,2 studied the effects of mercaptoethanol (HS-CH2 – CH2OH) and its oxidized counterpart, dithiodiglycol, on morphogenesis in a number of different systems (amphibian eggs, regenerating tadpoles and planarians, fragments of Acetabularia) : it was always found that mercaptoethanol inhibits morphogenesis, while dithiodiglycol has no effect or is even slightly stimulatory.

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References

  1. Brachet, J., and Delange-Cornil, M., “Developmental Biology”, 1, 79 (1959).

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  2. Brachet, J., J. Exp. Zool., 142, 115 (1960).

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  3. Henderson, R. F., and Eakin, R. E., J. Exp. Zool., 141, 175 (1959).

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  1. Laboratoire de Morphologie animale, Faculté des Sciences, Université libre de Bruxelles,

    J. BRACHET

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  1. J. BRACHET
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BRACHET, J. Morphogenetic Effects of Lipoic Acid on Amphibian Embryos. Nature 189, 156–157 (1961). https://doi.org/10.1038/189156a0

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