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An Iron Requirement for a Dissimilatory Nitrate Reductase in Neurospora crassa

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Abstract

NITRATE reduction in Neurospora is usually considered to be an assimilatory process. Nitrate reductase is a flavoprotein containing molybdenum, and the sequence of electron transfer has been determined as follows : where TPNH is reduced triphosphopyridine nucleotide and FAD is flavin-adenine-dinucleotide. It was shown that a deficiency of iron in the felts grown under aerobic conditions did not depress enzyme activity2,3. In this communication we report that Neurospora grown at low oxygen tensions dissimilates nitrate, and under these conditions nitrate reductase is dependent on iron as well as molybdenum for maximum activity.

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References

  1. Nicholas, D. J. D., and Nason, A., J. Biol. Chem., 211, 183 (1954).

    CAS  PubMed  Google Scholar 

  2. Nicholas, D. J. D., Nason, A., and McElroy, W. D., J. Biol. Chem., 207, 341 (1954).

    CAS  PubMed  Google Scholar 

  3. Nicholas, D. J. D., J. Sci. Food Agric., 8, 515 (1957).

    Google Scholar 

  4. Nicholas, D. J. D., and Fielding, A. H., J. Hort. Sci., 26, 125 (1951).

    Article  CAS  Google Scholar 

  5. Wosilait, W. D., and Nason, A., J. Biol. Chem., 206, 255 (1954).

    CAS  PubMed  Google Scholar 

  6. Lowry, O. H., Rosenbrough, W. J., Farr, A. L., and Randall, R. J., J. Biol. Chem., 193, 265 (1951).

    CAS  PubMed  Google Scholar 

  7. Fewson, C. A., and Nicholas, D. J. D., Biochem. J., 77, 3 (1960).

    Article  Google Scholar 

  8. Verhoeven, W., and Takeda, Y., in “Inorganic Nitrogen Metabolism”, edit. by McElroy and Glass, 159 (Johns Hopkins Univ. Press, Baltimore, 1956).

    Google Scholar 

  9. Sato, R., in “Inorganic Nitrogen Metabolism”, edit. by McElroy and Glass, 163 (Johns Hopkins Univ. Press, Baltimore, 1956.)

    Google Scholar 

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Author notes

  1. D. J. D. NICHOLAS: Member of the Scientific Staff of the Agricultural Research Council seconded to the University of Bristol.

Authors and Affiliations

  1. Chemical Microbiology Department, Long Ashton Research Station, University of Bristol,

    G. C. WALKER & D. J. D. NICHOLAS

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  1. G. C. WALKER
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  2. D. J. D. NICHOLAS
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WALKER, G., NICHOLAS, D. An Iron Requirement for a Dissimilatory Nitrate Reductase in Neurospora crassa . Nature 189, 141–142 (1961). https://doi.org/10.1038/189141a0

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