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Chromosomal Synthesis of Ribonucleic Acid as shown by Incorporation of Uridine labelled with Tritium

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Abstract

ACCORDING to a widely accepted view, the nucleus, and especially the nucleolus, is the main, or only, site of ribonucleic acid synthesis within the cell. This has been demonstrated by autoradiographic as well as by biochemical methods1. None of these investigations provide information as to the precise localization of structures within the nucleus which synthesize this acid, except the nucleolus, nor has it been shown that it is the nucleolar organizer which synthesizes the nucleolar ribonucleic acid.

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References

  1. Ficq, A., Arch. biol. (Liêge), 66, 509 (1955). Vincent, W. S., Intern. Rev. Cyt., 4, 269 (1955). Taylor, J. H., and McMaster, R. D., Genetics, 40, 600 (1955). Zalokar, M., Nature, 183, 1330 (1959).

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  2. Beermann, W., in “Developmental Cytology”, ed. D. Rudnick (New York, 1959).

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PELLING, G. Chromosomal Synthesis of Ribonucleic Acid as shown by Incorporation of Uridine labelled with Tritium. Nature 184, 655–656 (1959). https://doi.org/10.1038/184655a0

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