Abstract
As a result of previous work1–3, it has been concluded that there exist in α-casein, arginine and lysine residues carrying free α-amino groups and occupying N-terminal positions in open polypeptide chains. Estimates of the amounts of such arginine and lysine have however varied within wide limits. Furthermore, the α-casein employed in two at least of these investigations1,2 was prepared using a fractionation procedure now known to yield α-casein contaminated with k-casein.
Similar content being viewed by others
References
Mellon, E. F., Korn, A. H., and Hoover, S. R., J.A.C.S., 75, 1675 (1953).
Wissmann, H., and Nitschmann, H., Helv. Chim. Acta, 40, 356 (1957).
Ise, C. M., Diss. Abs., 19, 431 (1958).
Waugh, D. F., and von Hippel, P. H., J.A.C.S., 78, 4576 (1956).
Sanger, F., Biochem. J., 39, 507 (1945).
Levy, A. L., ‘Methods of Biochemical Analysis’, 2, 359 (1955).
Blackburn, S., and Lowther, A. G., Biochem. J., 48, 126 (1951).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MANSON, W. The N-Terminal Amino-acids of α-Casein. Nature 184, 1393–1394 (1959). https://doi.org/10.1038/1841393a0
Issue Date:
DOI: https://doi.org/10.1038/1841393a0
- Springer Nature Limited