Abstract
MALES with testicular hypoplasia (Klinefelter's syndrome) are of two cytological types. A minority has sex-chromatin-negative nuclei as have normal males, whereas the majority has sex-chromatin-positive nuclei as have normal females. The demonstration of the male-determining property of the mammalian Y-chromosome, proved for man1 and mouse2, had led to a clarification of the chromosomal status of sex-chromatin-positive Klinefelter individuals. They are XXY1,2
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References
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STERN, C. Colour-blindness in Klinefelter's Syndrome. Nature 183, 1452–1453 (1959). https://doi.org/10.1038/1831452a0
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DOI: https://doi.org/10.1038/1831452a0
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