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Pumilin, a New Antibiotic from Bacillus pumilus

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Abstract

ALTHOUGH it had been observed that strains of Bacillus pumilus produce substances with antibacterial activity, very little work has been done to isolate these substances. Gilliver1 observed the antibacterial activity of strains of B. pumilus, but made no attempt to isolate the active principles. Dvonch and Benedict2 isolated an antibacterial agent from a strain of B. pumilus which they showed to be similar to subtenolin, an antibiotic from B. subtilis. Borowski and others3 obtained an antibiotic, tetaine, from a strain of B. pumilus.

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References

  1. Gilliver, K., Brit. J. Exp. Path., 30, 214 (1949).

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  2. Dvonch, W., and Benedict, R. G., Antibiotics and Chemotherapy, 3, 192 (1953).

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  3. Borowski, E., et al., Chem. Abstracts, 47, 7,594 (1953); 48, 11,000 (1954).

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BHATE, D. Pumilin, a New Antibiotic from Bacillus pumilus . Nature 175, 816–817 (1955). https://doi.org/10.1038/175816a0

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