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Different-sized Infective Particles of Rift Valley Fever Virus

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Abstract

IN a recent communication, Polson1 indicated that the small animal viruses fall into definite weight-groups as calculated from their sedimentation constants, using the usual assumptions regarding density and particle shape. The particle weights are multiples of 1, 4, 16 and 64 of a basic unit, 12 mµ in diameter. Soluble antigen which itself is non-infective has been recovered from tissues infected with a variety of virus. It is of particular interest that those soluble antigens which have been measured are all approximately 12 mµ in diameter (influenza2, rabies3 and African horsesickness virus4).

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References

  1. Polson, A., Nature, 172, 1154 (1953).

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  2. Hoyle, L., Reed, R., and Astbury, W. T., Nature, 171, 256 (1953).

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  3. Polson, A., and Wessels, P. O., Proc. Soc. Exp. Biol. and Med., 84, 317 (1953).

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  4. Polson, A., and Madsen, T. (to be published).

  5. Polson, A., and Linder, A. M., Biochim. et Biophys. Acta, 11, 199 (1953).

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NAUDÉ, W., MADSEN, T. & POLSON, A. Different-sized Infective Particles of Rift Valley Fever Virus. Nature 173, 1051–1052 (1954). https://doi.org/10.1038/1731051a0

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