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Albumin: an Unsuspected Physiological Activity

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Abstract

WHEN testing various fractions of human blood plasma prepared by ether precipitation in the cold1, it was found that albumin had a definite effect on the perfused rabbit's heart. In view of this, and the fact that albumin has been used for clinical transfusion for some years without any evidence of ill effect, the reaction has been studied in some detail.

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References

  1. Kekwick, R. A., and Mackay, M. E. (to be published).

  2. Drury, A. N., Lutwak-Mann, C., and Solandt, O. M., Quart. J. Exp. Physiol., 27, 215 (1938).

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  3. Cohn, E. J., Oncley, J. L., Strong, L. E., Hughes, jun., W. L., and Armstrong, jun., H. S., J. Clin. Invest., 23, 674 (1944).

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BLEWETT, M., DRURY, A. & MACKAY, M. Albumin: an Unsuspected Physiological Activity. Nature 172, 79–80 (1953). https://doi.org/10.1038/172079b0

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