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Bacterial Enzyme Preparations oxidizing Inositol and their Inhibition by Colchicine

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Abstract

PREVIOUS studies in this laboratory have brought to light a number of regularities governing the oxidation of isomers of the inositol group by resting Acetobacter suboxydans1,2. If the hexahydroxy by cyclo-hexanes are formulated as existing in the chair configuration, the minimum steric requirements for the oxidation of the various isomers by the resting cells are described in the statement that only those hydroxyl groups are oxidized that are situated in a polar plane.

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FRANZL, R., CHARGAFF, E. Bacterial Enzyme Preparations oxidizing Inositol and their Inhibition by Colchicine. Nature 168, 955–957 (1951). https://doi.org/10.1038/168955b0

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