Skip to main content
SpringerLink
Log in

A Convenient Synthesis of Carbon-labelled Benzene

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

SEVERAL syntheses of benzene and its simple derivatives labelled in the nucleus with isotopic carbon have been described1–5. The aluminium-halide catalysed rearrangement of alkyl cyclopentanes to cyclohexanes6,7 affords an attractive route to benzene and its homologues, and we now present a preliminary report of an examination of this method as it applies to benzene itself.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Grosse, A. V., and Weinhouse, S., Science, 104, 402 (1946).

    Article  ADS  CAS  Google Scholar 

  2. Fields, M., Leaffer, M. A., and Rohan, J., Science, 109, 2820 (1949).

    Article  Google Scholar 

  3. Hughes, D. M., and Reid, J. C., J. Org. Chem., 14, 516 (1949). Schepartz, B., and Gurin, S., J. Biol. Chem., 180, 663 (1949).

    Article  CAS  Google Scholar 

  4. Tolbert, B. M., et al., quoted by Shelberg, W. E., and Tolbert, B. M., A.E.C.U. 178 (UCRL 281), U.S.A.E.C. (Feb. 1949).

  5. Crompton, C. E., and Woodruff, N. H., Nucleonics, 7 (3), 49; 7 (4), 44 (1950).

    CAS  PubMed  Google Scholar 

  6. cf. Nenitzescu, C. D., and Cantuniari, I. P., Ber., 66B, 1097 (1933). This paper contains a review of the early literature on this subject.

    Google Scholar 

  7. Glazebrook, A. L., and Lovell, W. G., J. Amer. Chem. Soc., 61, 1717 (1939).

    Article  Google Scholar 

  8. Nystrom, R. F., and Brown, W. G., J. Amer. Chem. Soc. 69, 2548 (1947).

    Article  CAS  Google Scholar 

  9. Zelinsky, N. D., Ber., 44, 3124 (1911); 45, 3678 (1912); 56, 1718 (1923); cf. also Plattner, P. A., “Newer Preparative Methods in Organic Chemistry”, 21 (Interscience Publishers, 1948).

    Google Scholar 

  10. Anal. Chem., 12, 175, 177 (1940).

  11. Hofmann, K. A., and Höchtlen, F., Ber., 36, 1149 (1903).

    Article  CAS  Google Scholar 

  12. Evans, R. F., Ormrod, O., Goalby, B. B., and Staveley, L. A. K., J. Chem. Soc., 3346 (1950).

Download references

Author information

Authors and Affiliations

  1. Chemical Research Laboratory, Teddington, Middlesex

    H. S. TURNER

Authors
  1. H. S. TURNER
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

TURNER, H. A Convenient Synthesis of Carbon-labelled Benzene. Nature 168, 73–74 (1951). https://doi.org/10.1038/168073b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/168073b0

  • Springer Nature Limited

Search

Navigation