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New Inhibitors of the First Stage of the Blood-clotting Process

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Abstract

IN the course of a study of the non-protein activator(s)1 of blood coagulation, which always occur(s) in the cephalin fraction of the phospholipids, without being identical with the classical cephalins, two inhibitors of the first stage of the clotting process, namely, glutamic acid and sphingosine, were discovered by means of paper chromatography. Both compounds are completely ineffective in the second stage of the clotting process.

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References

  1. Fischer, A., and Hecht, E., Biochem. Z., 269, 115 (1934).

    CAS  Google Scholar 

  2. Chargaff, E., Levine, C., and Green, Ch., J. Biol. Chem., 175, 67 (1948).

    CAS  Google Scholar 

  3. Tocantins, L. M., Carroll, R. T., and McBride, Th. J., Proc. Soc. Exp. Biol. Med., 68, 110 (1948).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Laboratory of Physiological Chemistry, University, Utrecht,

    E. HECHT

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  1. E. HECHT
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HECHT, E. New Inhibitors of the First Stage of the Blood-clotting Process. Nature 167, 279–280 (1951). https://doi.org/10.1038/167279b0

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