Abstract
WHEN deoxyribonucleic acid is subjected to the Feulgen reaction, the pigment which develops may be soluble in water or dilute acid, as the Stedmans1 have suggested. If deoxyribonucleohistone extracted from nuclei of beef spleen by the method of Mirsky and Pollister2 is treated in the same manner, the colour develops almost exclusively on the precipitate.
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References
Stedman, E., and Stedman, E., Nature, 152, 267 (1943).
Mirsky, A. E., and Pollister, A. W., J. Gen. Physiol., 30, 117 (1946).
Petermann, M. L., and Lamb, M., J. Biol. Chem., 176, 685 (1948).
Choudhuri, H. C., Nature, 152, 475 (1943).
Danielli, J. F., Symp. Soc. Exp. Biol., 1, 101 (1947).
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SIBATANI, A. Effects of Histone and other Proteins on the Feulgen Reaction. Nature 166, 355–356 (1950). https://doi.org/10.1038/166355a0
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DOI: https://doi.org/10.1038/166355a0
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