Skip to main content
SpringerLink
Log in

Inhibition of the Growth of Leuconostoc mesenteroides by the Toxic Factor from ‘Agenized’ Zein: Reversal by L-Glutamine

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

THE crystalline toxic factor originally isolated1 from zein treated with nitrogen trichloride causes epileptiform fits in certain animals and inhibits the growth of Leuconostoc mesenteroides P-602. The subsequent synthesis of the factor from methionine, reported3 from this laboratory, indicates that it probably has the structure CH3.SO(NH).CH2.CH2.CH(NH2)COOH which, formally, has some resemblance to that of glutamine.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Bentley, H. R., McDermott, E. E., Pace, J., Whitehead, J. K., and Moran, T., Nature, 164, 438 (1949); 165, 150 (1950).

    Article  ADS  CAS  Google Scholar 

  2. Heathcote, J. G., Nature, 164, 439 (1949).

    Article  ADS  CAS  Google Scholar 

  3. Bentley, H. R., McDermott, E. E., and Whitehead, J. K., Nature, 165, 735 (1950).

    Article  ADS  CAS  Google Scholar 

  4. Waelsch, H., Owades, P., Miller, H. K., and Borek, E., J. Biol. Chem., 166, 273 (1946).

    CAS  PubMed  Google Scholar 

  5. Roper, J. A., and McIlwain, H., Biochem. J., 42, 485 (1948).

    Article  CAS  Google Scholar 

  6. McIlwain, H., Roper, J. A., and Hughes, D. E., Biochem. J., 42, 492 (1948).

    Article  CAS  Google Scholar 

  7. Archbald, R. M., Chem Rev., 37, 161 (1945).

    Article  Google Scholar 

  8. Price, J. C., Waelsch, H., and Putnam, T. J., J. Amer. Med. Assoc., 122, 1153 (1943).

    Article  CAS  Google Scholar 

  9. Waelsch, H., and Price, J. C., Arch. Neurol. and Psychiat., 51, 393 (1944).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Research Association of British Flour Millers, Cereals Research Station, Old London Road, St. Albans

    J. G. HEATHCOTE & J. PACE

Authors
  1. J. G. HEATHCOTE
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. PACE
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

HEATHCOTE, J., PACE, J. Inhibition of the Growth of Leuconostoc mesenteroides by the Toxic Factor from ‘Agenized’ Zein: Reversal by L-Glutamine. Nature 166, 353–354 (1950). https://doi.org/10.1038/166353a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/166353a0

  • Springer Nature Limited

This article is cited by

Search

Navigation