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An Adaptation Mechanism of the Organism to Damage : the Role of ‘Resistine'

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Abstract

WE have shown by experiments on rats and mice, using the Indian ink method devised by Jancsó1, that the exposure of the organism to various damaging stimuli (injection of formaldehyde, adrenaline, agmatine, exposure to cold, X-ray irradiation, starving, surgical trauma, etc.) leads always to local and often general release of histamine. The site of histamine liberation looked as if it had been painted with Indian ink.

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References

  • Jancsó, N., Nature, 160, 227 (1947).

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  • Karády, S., and Földi, M., Ber. d. g. Phys. u. exp. Pharm., 134, 185 (1943).

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Authors and Affiliations

  1. Department of Internal Clinic and Pharmacology, University, Szeged, Hungary

    S. KARÁDY & A. KOVÁCS

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  1. S. KARÁDY
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  2. A. KOVÁCS
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KARÁDY, S., KOVÁCS, A. An Adaptation Mechanism of the Organism to Damage : the Role of ‘Resistine'. Nature 161, 688 (1948). https://doi.org/10.1038/161688a0

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