Abstract
Genetic recombination during meiosis is associated with the generation and repair of DNA lesions. Surprisingly, some of the genes involved in DNA repair in Drosophila are also required to pattern the developing egg. New data begin to reveal the basis for this connection.
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References
Roeder, G. Genes Dev. 11, 2600–2621 (1997).
Chu, S. & Herskowitz, I. Mol. Cell 1, 685–696 (1998).
Ghabrial, A. & Schüpbach, T. Nature Cell Biol. 1, 354–357 (1999).
Tomancak, P., Guichet, A., Zavorsky, P. & Ephrussi, A. Development 125, 1723–1732 (1998).
Styhler, S., Nakamura, A., Swan, A., Suter, B. & Lasko, P. Development 125, 1569– 1578 (1998).
González-Reyes, A., Elliott, H. & St Johnston, D. Nature 375, 654– 658 (1995).
Roth, S., Neuman-Shilberberg, F., Barcelo, G. & Schüpbach, T. Cell 81, 967–978 ( 1995).
G onzález-Reyes, A., Elliott, H. & St Johnston, D. Development 124, 4927– 4937 (1997).
Ghabrial, A., Ray, R. & Schüpbach, T. Genes Dev. 12, 2711– 2723 (1998).
Boyd, J., Golino, M., Shaw, K., Osgood, C. & Green, M. Genetics 97, 607– 623 (1981).
McKim, K. & Hayashi-Hagihara, A. Genes Dev. 12, 2932–2942 (1998).
Hari, K. et al. Cell 82, 815–821 (1995).
Sibon, O., Laurençon, A., Hawley, R. & Theurkauf, W. Curr. Biol. 9, 302–312 ( 1999).
Gillespie, D. & Berg, C. Genes Dev. 9, 2495–2508 (1995).
de Cuevas, M. & Spradling, A. Annu. Rev. Genet. 31, 405–428 (1997).
Carpenter, A. in Germline Development (eds Marsh, J. & Goode, J.) 223– 246 (John Wiley & Sons, Chichester, 1994).
Carpenter, A. Chromosoma 51, 157–182 ( 1975).
de Cuevas, M. & Spradling, A. Development 125, 2781–2799 (1998).
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González-Reyes, A. DNA repair and pattern formation come together. Nat Cell Biol 1, E150–E152 (1999). https://doi.org/10.1038/14103
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DOI: https://doi.org/10.1038/14103
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