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γδ T cells provide a breath of fresh air for asthma research

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Abstract

γδ T cells downregulate airways responsiveness to allergen challenge, possibly by controlling the 'repair' response of the airway epithelium to αβ T cell-mediated damage (pages 1150–1156).

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Figure 1: Development of airway hyperresponsiveness in atopic asthma.

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Authors and Affiliations

  1. TVW Telethon Institute for Child Health Research, Perth, Western Australia

    Patrick G. Holt & P. D. Sly

  2. The Department of Microbiology, Division of Cell Biology, University of Western Australia, PO Box 855, West Perth, Western Australia, 6872, Australia

    Patrick G. Holt

  3. The Department of Pediatrics, Division of Cell Biology, University of Western Australia, PO Box 855, West Perth, 6872, Western Australia, Australia

    P. D. Sly

Authors
  1. Patrick G. Holt
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  2. P. D. Sly
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Holt, P., Sly, P. γδ T cells provide a breath of fresh air for asthma research . Nat Med 5, 1127–1128 (1999). https://doi.org/10.1038/13447

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