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A handle on NSF

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Abstract

New and exciting insights into the mechanism of membrane fusion emerge from the structures of Sec17 and of the amino-terminal domain of NSF, two proteins that play a central part in vesicular trafficking in organisms from yeast to man.

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Figure 1: Model for the assembly of the 20S particle from its components.

References

  1. May, A. P., Misura, K. M. S., Whiteheart, S. W. & Weis, W. I. Nature Cell Biol. 1, 175–182 (1999).

    Article  CAS  Google Scholar 

  2. Yu, R. C., Jahn, R. & Brunger, A. T. Mol. Cell 3, 97–107 (1999).

    Article  Google Scholar 

  3. Rice, L. M. & Brunger, A. T. Mol. Cell 3, 85–95 (1999).

    Article  Google Scholar 

  4. Söllner, T. et al. Nature 362, 318–324 (1993).

    Article  Google Scholar 

  5. Lenzen, C. U., Steinmann, D., Whiteheart, S. W. & Weis, W. I. Cell 94, 525–536 (1998).

    Article  CAS  Google Scholar 

  6. Poirier, M. A. et al. Nature Struct. Biol. 5, 765–769 (1998).

    Article  CAS  Google Scholar 

  7. Sutton, R. B., Fasshauer, D., Jahn, R. & Brunger, A. T. Nature 395, 347–353 (1998).

    Article  CAS  Google Scholar 

  8. Yu, R. C., Hanson, P. I., Jahn, R. & Brunger, A. T. Nature Struct. Biol. 5, 803–811 (1998).

    Article  CAS  Google Scholar 

  9. Patel, S. K. & Latterich, M. Trends Cell Biol. 8, 65–71 (1998).

    Article  CAS  Google Scholar 

  10. Neuwald, A. F. Structure 7, R19–R23 (1999).

    Article  CAS  Google Scholar 

  11. Lin, J. W. & Sheng, M. Neuron 21, 267–270 (1998).

    Article  CAS  Google Scholar 

  12. Haas, A. Trends Cell Biol. 8, 471–473 (1998).

    Article  CAS  Google Scholar 

  13. Lefkowitz, R. J. J. Biol. Chem. 273, 18677–18680 (1998).

    Article  CAS  Google Scholar 

  14. McDonald, P. H. et al. J. Biol. Chem. 274, 10677–10680 (1999).

    Article  CAS  Google Scholar 

  15. Steel, G. J., Tagaya, M. & Woodman, P. G. EMBO J. 15, 745–752 (1996).

    Article  CAS  Google Scholar 

  16. Otter-Nilsson, M., Hendriks, R., PecheurHuet, E. L., Hoekstra, D. & Nilsson, T. EMBO J. 18, 2074–2083 (1999).

    Article  CAS  Google Scholar 

  17. Müller, J. M. M. et al. Nature Cell Biol. (in the press).

  18. Hanson, P. I., Roth, R., Morisaki, H., Jahn, R. & Heuser, J. E. Cell 90, 523–535 (1997).

    Article  CAS  Google Scholar 

  19. Hohl, T. M. et al. Mol. Cell 2, 539–548 (1998).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK

    David J. Owen

  2. Molecular NeuroPathobiology Laboratory, Imperial Cancer Research Fund, 44 Lincoln’s Inn Fields, London, WC2A 3PX, UK

    Giampietro Schiavo

Authors
  1. David J. Owen
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  2. Giampietro Schiavo
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Correspondence to Giampietro Schiavo.

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Owen, D., Schiavo, G. A handle on NSF. Nat Cell Biol 1, E127–E128 (1999). https://doi.org/10.1038/12959

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