Abstract
Semaphorins are known to repel growth cones of developing axons, but a study of the grasshopper limb bud shows that they can also serve as attractive guidance cues.
References
Mueller, B. K. Annu. Rev. Neurosci. 22, 351–388 (1999).
Mark, M. D., Lohrum, M. & Puschel, A. W. Cell Tissue Res. 290, 299– 306 (1997).
Wong, J. T. W., Wong, S. T. M. & O'Connor, T. P. Nat. Neurosci. 2, 798– 803 (1999).
Semaphorin Nomenclature Committee Cell 97, 551–552 (1999).
Adams, R. H., Lohrum, M., Klostermann, A., Betz, H. & Puschel, A. W. EMBO J. 16, 6077–6086 (1997).
Bagnard, D., Lohrum, M., Uziel, D., Puschel, A. W. & Bolz, J. Development 125, 5043– 5053 (1998).
Yu, H.-H., Araj, H. H., Ralls, S. A. & Kolodkin, A. L. Neuron 20, 207–220 (1998).
Wong, J. T., Yu, W. T. & O'Connor, T. P. Development 124, 3597– 3607 (1997).
Kolodkin, A. L. et al. Neuron 9, 831–845 (1992).
Isbister, C. M., Tsai, A., Wong, S. T., Kolodkin, A. L. & O'Connor, T. P. Development 126, 2007– 2019 (1999).
Takahashi, T., Nakamura, F., Jin, Z., Kalb, R. G. & Strittmatter, S. M. Nat. Neurosci. 1, 487– 493 (1998).
Stein, E. et al. Genes Dev. 12, 667–678 (1998).
Torres, R. et al. Neuron 21, 1453–1463 (1998).
Brückner, K. et al. Neuron 22, 511–524 (1999).
Wang, L. H., Kalb, R. G. & Strittmatter, S. M. J. Biol. Chem. 274, 14137– 14146 (1999).
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Püschel, A. Semaphorins: repulsive guidance molecules show their attractive side . Nat Neurosci 2, 777–778 (1999). https://doi.org/10.1038/12140
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DOI: https://doi.org/10.1038/12140
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