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MEK Wars, a new front in the battle against cancer

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Abstract

A specific inhibitor of the mitogen-activated protein kinase (MAPK or ERK) pathway is introduced as a new member in the growing search for cytostatic drugs that block tumor growth (pages 810–816).

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Figure 1: Intracellular signaling pathways that mediate MAPK (ERK1/2) activation after growth factor stimulation.

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Duesbery, N., Webb, C. & Vande Woude, G. MEK Wars, a new front in the battle against cancer. Nat Med 5, 736–737 (1999). https://doi.org/10.1038/10457

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