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How BAD phosphorylation is good for survival

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Abstract

BAD is a pro-apoptotic member of the Bcl-2 family that is tightly regulated by survival factors. Several major signalling pathways influence cell death through their direct effects on the phosphorylation state of BAD.

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Figure 1: Regulation of BAD phosphorylation.

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Authors and Affiliations

  1. Imperial Cancer Research Fund, 44 Lincoln’s Inn Fields, London, WC2A 3PX, UK

    Julian Downward

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  1. Julian Downward
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Correspondence to Julian Downward.

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Downward, J. How BAD phosphorylation is good for survival. Nat Cell Biol 1, E33–E35 (1999). https://doi.org/10.1038/10026

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