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Stretching and visualizing titin molecules: combining structure, dynamics and mechanics

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Abstract

The details of the global and local structure and function of titin, a gaint filamentous intrasarcomeric protein are largely undiscovered. Here we dicuss a combination of bulk-solution and novel single-molecule techniques that may lend unique insights into titin's molecular dynamic, structural and mechanical characteristics.

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  1. Department of Biophysics, University of Pécs, Medical School Pécs, Szigeti ut 12, Pécs, H-7624, Hungary

    Miklós S. Z. Kellermayer & László Grama

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  1. Miklós S. Z. Kellermayer
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  2. László Grama
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Kellermayer, M.S.Z., Grama, L. Stretching and visualizing titin molecules: combining structure, dynamics and mechanics. J Muscle Res Cell Motil 23, 499–511 (2002). https://doi.org/10.1023/A:1023414624092

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