Abstract
Mixed interval-censored (MIC) data consist of n intervals with endpoints L i and R i , i = 1, ..., n. At least one of them is a singleton set and one is a finite non-singleton interval. The survival time X i is only known to lie between L i and R i , i = 1, 2, ..., n. Peto (1973, Applied Statistics, 22, 86–91) and Turnbull (1976, J. Roy. Statist. Soc. Ser. B, 38, 290–295) obtained, respectively, the generalized MLE (GMLE) and the self-consistent estimator (SCE) of the distribution function of X with MIC data. In this paper, we introduce a model for MIC data and establish strong consistency, asymptotic normality and asymptotic efficiency of the SCE and GMLE with MIC data under this model with mild conditions.
Similar content being viewed by others
References
Ayer, M., Brunk, H. D., Ewing, G. M., Reid, W. T. and Silverman, E. (1955). An empirical distribution function for sampling incomplete information, Ann. Math. Statist., 26, 641-647.
Chang, M. N. and Yang, G. (1987). Strong consistency of a self-consistent estimator of the survival function with doubly-censored data, Ann. Statist., 15, 1536-1547.
Finkelstein, D. M. and Wolfe, R. A. (1985). A semiparametric model for regression analysis of interval-censored failure time data, Biometrics, 41, 933-945.
Gentleman, R. and Geyer, C. J. (1994). Maximum likelihood for interval censored data: Consistency and computation, Biometrika, 81, 618-623.
Groeneboom, P. (1996). Inverse problem in statistics, Proceedings of the St. Flour Summer School in Probability, 1994, Lecture notes in Math., No. 1648, Springer, Berlin.
Groeneboom, P. and Wellner, J. A. (1992). Information Bounds and Nonparametric Maximum Likelihood Estimation, Birkhäuser, Basel.
Gu, M. G. and Zhang, C. H. (1993). Asymptotic properties of self-consistent estimator based on doubly censored data, Ann. Statist., 21, 611-624.
Huang, J. (1996). Efficient estimation for proportional hazards models with interval censoring, Ann. Statist., 24, 540-568.
Huang, J. (1999). Asymptotic properties of nonparametric estimation based on partly interval-censored data, Statist. Sinica, 9, 501-520.
Li, L. X., Watkins, T. and Yu, Q. Q. (1997). An EM algorithm for smoothing the self-consistent estimator of survival functions with interval-censored data, Scand. J. Statist., 24, 531-542.
Odell, P. M., Anderson, K. M. and D'Agostino, R. B. (1992). Maximum likelihood estimation for interval-censored data using a Weibull-based accelerated failure time model, Biometrics, 48, 951-959.
Peto, R. (1973). Experimental survival curves for interval-censored data, App. Statist., 22, 86-91.
Petroni, G. R. and Wolfe, R. A. (1994). A two-sample test for stochastic ordering with interval-censored data, Biometrics, 50, 77-87.
Pollard, D. (1984). Convergence of Stochastic Processes, Springer, New York.
Schick, A. and Yu, Q. Q. (2000). Consistency of the GMLE with mixed case interval-censored data, Scand. J. Statist., 27, 45-55.
Turnbull, B. W. (1976). The empirical distribution function with arbitrary grouped, censored and truncated data, J. Roy. Statist. Soc. Ser. B., 38, 290-295.
Van De Geer, S. (1996). Rates of convergence for the maximum likelihood estimator in mixture models, J. Nonparametr. Statist., 6, 293-310.
Wellner, J. A. (1995). Interval censoring case 2: alternative hypotheses, Analysis of Censored Data, Proceedings of the workshop on analysis of censored data, December 28, 1994–January 1, 1995, University of Pune, Pune, India, IMS Lecture Notes-Monograph Series, Vol. 27, Hayward, Carifornia.
Wellner, J. A. and Zhan, Y. (1997). A hybrid algorithm for computation of the NPMLE from censored data, J. Amer. Statist. Assoc., 92, 945-959.
Yu, Q. Q. and Li, L. X. (1994). On the strong consistency of the product limit estimator. Sankhyā Ser. A, 56, 416-430.
Yu, Q. Q. and Li, L. X. (1999). Asymptotic properties of the GMLE of self-consistent estimators with doubly-censored data, Acta Math. Sinica. (accepted).
Yu, Q. Q., Li, L. X. and Wong, G. Y. C. (1998a). Asymptotic variance of the GMLE of a survival function with interval-censored data, Sankhyā, Ser. A, 60, 184-197.
Yu, Q. Q., Schick, A., Li, L. X. and Wong, G. Y. C. (1998b). Asymptotic properties of the GMLE in the case 1 interval censorship model with discrete inspection times, Canad. J. Statist., 26, 619-627.
Yu, Q. Q., Schick, A., Li, L. X. and Wong, G. Y. C. (1998c). Asymptotic properties of the GMLE of a survival function with case 2 interval-censored data, Statist. Probab. Lett., 37, 223-228.
Yu, Q. Q., Li, L. X. and Wong, G. Y. C. (2000). On consistency of the self-consistent estimator of survival functions with interval-censored data, Scand. J. Statist., 27, 35-44.
Author information
Authors and Affiliations
About this article
Cite this article
Yu, Q., Wong, G.Y.C. & Li, L. Asymptotic Properties of Self-Consistent Estimators with Mixed Interval-Censored Data. Annals of the Institute of Statistical Mathematics 53, 469–486 (2001). https://doi.org/10.1023/A:1014656726982
Issue Date:
DOI: https://doi.org/10.1023/A:1014656726982