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Positron Emission Tomography and Random Coefficients Regression

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Abstract

We further explore the relation between random coefficients regression (RCR) and computerized tomography. Recently, Beran et al. (1996, Ann. Statist., 24, 2569–2592) explored this connection to derive an estimation method for the non-parametric RCR problem which is closely related to image reconstruction methods in X-ray computerized tomography. In this paper we emphasize the close connection of the RCR problem with positron emission tomography (PET). Specifically, we show that the RCR problem can be viewed as an idealized (continuous) version of a PET experiment, by demonstrating that the nonparametric likelihood of the RCR problem is equivalent to that of a specific PET experiment. Consequently, methods independently developed for either of the two problems can be adapted from one problem to the other. To demonstrate the close relation between the two problems we use the estimation method of Beran, Feuerverger and Hall for image reconstruction in PET.

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Feuerverger, A., Vardi, Y. Positron Emission Tomography and Random Coefficients Regression. Annals of the Institute of Statistical Mathematics 52, 123–138 (2000). https://doi.org/10.1023/A:1004141117010

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