Boron in human and animal nutrition
- Forrest H. Nielsen
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This review describes the findings from human and animal studies indicating that B is a dynamic trace element which, in physiological amounts, can affect the metabolism or utilisation of numerous other substances involved in life processes including macrominerals, energy substrates such as triglycerides and glucose, nitrogen containing substances such as amino acids and proteins, reactive oxygen species, and estrogen. Through these effects, B can affect the function or composition of several body systems, including the brain, skeleton and immune system, generally in a beneficial fashion. Moreover, homeostatic mechanisms apparently exist for B because it is rapidly excreted in the urine, does not accumulate in tissues, and is maintained in a relatively narrow range of concentrations in blood of healthy individuals. Thus, even though B has not been conclusively established as essential because a biochemical function for it has not been identified, its beneficial actions suggest that an intake of over 1 mg day-1 (but probably not more than 13 mg day-1) is desirable; diets low in fruits, vegetables, legumes and nuts may not provide this amount of B. Boron may be of more practical nutritional importance than currently acknowledged.
- Aasen G H and Hunt C D 1993 Biochemical responses to dietary boron over a 20-fold physiological range in the male rats. Proc. ND Acad. Sci. 47, 57.
- Anderson D L, Cunningham WC and Lindstrom T R 1994 Concentrations and intakes of H, B, S, K, Na, Cl, and NaCl in foods. J. Food Comp. Anal. 7, 59-82.
- Bai Y and Hunt CD 1995a Dietary boron alleviates adjuvant-induced arthritis (AIA) in rats. FASEB J. 9, A576.
- Bai Y and Hunt C D 1995b Dietary boron improves indices of marginal vitamin D status but does not substitute for the vitamin. New Approaches, Endpoints, and Paradigms for RDAs of Mineral Elements Abstracts, p. 29. University of North Dakota and USDA, ARS, Grand Forks Human Nutrition Research Center, Grand Forks, ND.
- Bai Y and Hunt C D 1996a Absorption and distribution of boron in rats following a single oral administration of boron. Proc. ND Acad. Sci. 50, 53.
- Bai Y and Hunt C D 1996b Dietary boron (B) increases serum antibody concentrations in rats immunised with heat-killed mycobacterium tuberculosis (MT). FASEB J. 10, A819.
- Bakken N A and Hunt C D 1995 Dietary boron affects plasma 1, 25-dihdroxyvitamin D (1, 25 Vit D) concentrations and peak pancreatic insulin secretion in the chick. New Approaches, Endpoints, and Paradigms for RDAs of Mineral Elements Abstracts, p. 30. University of North Dakota and USDA, ARS, Grand Forks Human Nutrition Research Center, Grand Forks, ND.
- Blevins D G and Lukaszewski K M 1994 Proposed physiological functions of boron in plants pertinent to animal and human metabolism. Environ. Health Perspect. 102 (Suppl 7), 31-33.
- Follis R H Jr 1947 The effect of adding boron to a potassium-deficient diet in the rat. Am. J. Physiol. 150, 520-522.
- Gordon A S, Prichard J S and Freedman MH 1973 Seizure disorders and anaemia associated with chronic borax intoxication. Can. Med. Assoc J. 108, 719-721.
- Gordon V (Ed) 1987 The case of the toxic life-preserver. Borax Review No. 2, 10-12.
- Health Effects of Boron 1994 Environ. Health Perspect. 102 (Suppl 7), 150.
- Hegsted M, Keenan M J, Siver F and Wozniak P 1991 Effect of boron on vitamin D deficient rats. Biol. Trace Elem. Res. 26, 243-255.
- Herbel J L and Hunt C D 1992 Dietary boron modifies the effects of thiamine nutriture in the male rat. Proc. ND Acad. Sci. 46, 71.
- Hove E, Elvehjem C A and Hart E B 1939 Boron in animal nutrition. Am. J. Physiol. 127, 689-701.
- Hunt C D 1989 Dietary boron modified the effects of magnesium and molybdenum on mineral metabolism in the cholecalciferol-deficient chick. Biol. Trace Elem. Res. 22, 201-220.
- Hunt C D 1993 Boron. In Encyclopedia of Food Science, Food Technology and Nutrition, vol 1. Eds. R Macrae, R K Robinson and M J Sadler. pp 440-447. Academic Press, London.
- Hunt C D 1994 The biochemical effects of physiological amounts of dietary boron in animal nutrition models. Environ. Health Perspect. 102 (Suppl 7), 35-43.
- Hunt C D 1997 Boron and vitamin D deficiencies affect hepatic glycolytic metabolite concentrations in the chick. In Ninth International Symposium on Trace Elements in Man and Animals, TEMA-9. Eds. P W F Fischer, M R L'Abbe, K A Cockell and R S Gibson. pp 599-601. NRC Research Press, Ottawa, Ontario, Canada.
- Hunt C D and Herbel J F 1991-1992 Boron affects energy-metabolism in the streptozotocin-injected, vitamin D3-deprived rat. Magnesium Trace Elem. 10, 374-386.
- Hunt C D and Herbel J L 1993 Physiological amounts of dietary boron improve growth and indicators of physiological status over a 20-fold range in the vitamin D3-deficient chick. In: Trace Element Metabolism in Man and Animals, TEMA-8. Eds. M Anke, D Meissner and C F Mills. pp 714-718. Verlag Media Touristik, Gersdorf.
- Hunt C D and Nielsen F H 1981 Interaction between boron and cholecalciferol in the chick. In Trace Element Metabolism in Man and Animals (TEMA-4). Eds. J McC Howell, J M Gawthorne and C L White. pp 597-600. Australian Academy of Science, Canberra, Australia.
- Hunt C D and Nielsen F H 1987 Interactions among dietary boron, magnesium, and cholecalciferol in the chick. Proc. ND Acad. Sci. 41, 50.
- Hunt C D, Herbel J L and Idso J P 1994 Dietary boron modifies the effects of vitamin D3 nutrition on indices of energy substrate utilisation and mineral metabolism in the chick. J. Bone Min. Res. 9, 171-182.
- Hunt C D, Herbel J L and Nielsen F H 1997 Metabolic responses of postmenopausal women to supplemental dietary boron and aluminium during usual and low magnesium intake: Boron, calcium and magnesium absorption and retention and blood mineral concentrations. Am. J. Clin. Nutr. 65, 803-813.
- Hunt C D, Shuler T R and Mullen LM 1991 Concentration on boron and other elements in human foods and personal-care products. J. Am. Diet Assoc. 91, 558-568.
- Iyengar G V, Clarke W B and Downing R G 1990 Determination of boron and lithium in diverse biological matrices using neutron activation-mass spectrometry (NA-MS). Fres. J. Anal. Chem. 338, 562-566.
- Jansen J A, Schou J S and Aggerbeck B 1984 Gastro-intestinal absorption and in vitro release of boric acid from watere-mulsifying ointments. Food Chem. Toxicol. 22, 49-53.
- King N, Odom TW, Sampson H W and Yersin A G 1991 The effect of in vivo boron supplementation on bone mineralisation of the vitamin D-deficient chicken embryo. Biol. Trace Elem. Res. 31, 223-233.
- Linden C H, Hall A H, Kulig K W and Rumack B H 1986 Acute ingestions of boric acid. Clin. Toxicol. 24, 269-279.
- Newnham R E 1994 Essentiality of boron for healthy bones and joints. Environ. Health Perspect. 102 (Suppl 7), 83-85.
- Nielsen F H 1989 Dietary boron affects variables associated with coppermetabolism in humans. In 6th International Trace Element Symposium, vol. 4. Eds. M Anke, W Baumann, H Braunlich, C Bruckner, B Groppel and M Grun. pp 1106-1111. Friedrich-Schiller-Universitat, Jena.
- Nielsen F H 1991 Nutritional requirements for boron, silicon, vanadium, nickel and arsenic: current knowledge and speculation. FASEB J. 5, 2661-2667.
- Nielsen F H 1994 Biochemical and physiologic consequences of boron deprivation in humans. Environ. Health Perspect. 102 (Suppl 7), 59-63.
- Nielsen FH 1996 Dietary supplementation of physiological amounts of boron increases plasma and urinary boron of perimenopausal women. Proc. ND Acad. Sci. 50, 52.
- Nielsen F H, Mullen L M and Gallagher S K 1990 Effect of boron depletion and repletion on blood indicators of calcium status in humans fed a magnesium-low diet. J. Trace Elem. Exp. Med. 3, 45-54.
- Nielsen F H, Mullen LM and Nielsen E J 1991 Dietary boron affects blood cell counts and haemoglobin concentrations in humans. J. Trace Elem. Exp. Med. 4, 211-223.
- Nielsen F H, Gallagher S K, Johnson L K and Nielsen E J 1992 Boron enhances and mimics some effects of estrogen therapy in postmenopausal women. J. Trace Elem. Exp. Med. 5, 237-246.
- Orent-Keiles E 1941 The role of boron in the diet of the rat. Proc. Soc. Exp. Biol. Med. 44, 199-202.
- Penland J G 1990 Dietary boron affects brain in mature Long-Evans rats. Proc. ND Acad. Sci. 44, 78.
- Penland J G 1994 Dietary boron, brain function, and cognitive performance. Environ. Health Perspect. 102 (Suppl 7), 65-72.
- Penland J G and Eberhardt M J 1993 Effects of dietary boron and magnesium on brain function of mature male and female Long-Evans rats. J. Trace Elem. Exp. Med. 6, 53-64.
- Pinto J, Huang Y P, McConnell R J and Rivlin R S 1978 Increased urinary riboflavin excretion resulting from boric acid ingestion. J. Lab. Clin. Med. 92, 126-134.
- Ploquin J 1967 Le bore dans l'alimentation. Bull. Soc. Sci. Hyg. Aliment. 55, 70-113.
- Rainey C J, Christensen R E, Nyquist L A, Strong P L and Coughlin J R 1996 Boron daily intake from the American diet. FASEB J. 10, A785.
- Shah S A and Vohora S B 1990 Boron enhances anti-arthritic effects of garlic oil. Fitoterapia 61, 121-126.
- Shuler T R, Pootrakul P, Yarnsukon P and Nielsen F H 1990 Effect of thalassemia/haemoglobin E disease on macro, trace, and ultra-trace element concentrations in humans tissues. J. Trace Elem. Med. 3, 31-43.
- Skinner J T and McHargue J S 1945 Response of rats to boron supplements when fed rations low in potassium. Am. J. Physiol. 143, 385-390.
- Sommer A L and Lipman C B 1926 Evidence of the indispensable nature of zinc and boron for higher green plants. Plant Physiol. 1, 231-249.
- Teresi J D, Hove E, Elvehjem C A and Hart E B 1944 Further study of boron in the nutrition of rats. Am. J. Physiol. 140, 513-518.
- Travers RL, Rennie G C and Newnham RE 1990 Boron and arthritis: the results of a double-blind pilot study. J. Nutr. Med. 1, 127-132.
- UK Ministry of Agriculture, Fisheries and Food 1991 Household food consumption and expenditure 1991. Annual Report of the National Food Survey Committee, HMSO, Table B1.
- Vanderpool R A, Hoff D and Johnson P E 1994 Use of inductively coupled plasma-mass spectrometry in boron-10 stable isotope experiments with plants, rats and humans. Environ. Health Perspect. 102 (Suppl 7), 13-20.
- Ward N I 1993 Boron levels in human tissues and fluids. In Trace Elements in Man and Animals, TEMA-8. Eds. M Anke, D Meissner and C F Mills. pp 724-728. Verlag Media Touristik, Gersdorf.
- Warington K 1923 The effect of boric acid and borax on the broad bean and certain other plants. Ann. Bot. 37, 629-672.
- WHO/FAO/IAEA: 1996 Trace Elements in Human Nutrition and Health. World Health Organisation, Geneva. pp. 175-179.
- Wiley HW 1904 Influence of food preservatives and artificial colours on digestion and health. I. Boric acid and borax. US Department of Agriculture Bulletin No. 84, Pt, 1, Government Printing Office, Washington, DC.
- Boron in human and animal nutrition
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