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Extracellular Tremella polysaccharides: structure, properties and applications

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Abstract

Tremella sp. is a yeast-like fungus from which polysaccharides can be isolated from either the yeast or the fungus phase, depending on the species. All of the polymers synthesized by these organisms consist of a mannan backbone to which small xylose side chains and glucuronic acid are attached. The main interest in these glucuronoxylomannans is their application in medicine to enhance the immune system.

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References

  • Abercrombie MJ,Jones JKN,Lock MV,Perry MB,Stoodley RJ (1960) The polysaccharides of Cryptococcus laurentii (NRRL Y-1401). Can. J. Chem. 38: 1617-1624.

    Google Scholar 

  • Bandoni RJ,Boekhout T (1998) Tremelloid genera with yeast phases. In: Kurtzmann CP,Fell JW, eds. The Yeasts-A Taxonomic Study, 4th edn. Amsterdam: Elsevier, pp. 705-717.

    Google Scholar 

  • Boekhout T,Bandoni RJ,Fell JW,Kwon-Chung KJ (1998) Discussion of teleomorphic and anamorphic genera of heterobasidiomycetous yeasts. In: Kurtzmann CP,Fell JW, eds. The Yeasts-A Taxonomic Study, 4th edn. Amsterdam: Elsevier, pp. 609-625.

    Google Scholar 

  • Cadmus MC,Lagoda AA,Anderson RF (1962) Production of a new polysaccharide with Cryptococcus laurentii var. flavescens. Appl. Microbiol. 10: 153-156.

    Google Scholar 

  • Chang H-Y (1998) Mycelial properties of Tremella fuciformis and Hypoxylon sp. Korean J. Mycol. 26: 321-326.

    Google Scholar 

  • Cherniak R,Jones RG,Slodki ME (1988) Type-specific polysaccharides of Cryptococcus neoformans. N.M.R.-spectral study of a glucuronomannan chemically derived from a Tremella mesenterica exopolysaccharide. Carbohydr. Res. 182: 227-239.

    Google Scholar 

  • Cheung PCK (1996) The hypercholesterolemic effect of two edible mushrooms: Auricularia auricula (tree-ear) and Tremella fuciformis (white jelly-leaf) in hypercholesterolemic rats. Nutr. Res. 16: 1721-1725.

    Google Scholar 

  • De Baets S,Vandamme EJ (1998) Polymers from fungi and yeasts and their technical and medical application. Biologi Italiani 2: 13-17.

    Google Scholar 

  • De Baets S,Vandamme EJ (1999) Yeast as producers of polysaccharides with novel application potential. SIM News 49: 321-328.

    Google Scholar 

  • Fraser CG,Jennings HJ (1971) A glucan from Tremella mesenterica NRRL Y-6158. Can. J. Chem. 49: 1804-1807.

    Google Scholar 

  • Fraser CG,Jennings HJ,Moyna P (1973) Structural analysis of an acidic polysaccharide from Tremella mesenterica NRRL Y-6158. Can. J. Biochem. 51: 219-224.

    Google Scholar 

  • Gao Q,Berntzen G,Jiang R,Killie MK,Seljejid R (1998) Conjugates of Tremella polysaccharides with microbeads and their TNF-stimulating activity. Planta Med. 64: 551-554.

    Google Scholar 

  • Gao Q,Jiang R,Chen H,Jensen E,Seljejid R (1996a) Characterization and cytokine stimulating activities of heteroglycans from Tremella fuciformis. Planta Med. 62: 297-302.

    Google Scholar 

  • Gao Q,Seljejid R,Chen H,Jiang R (1996b) Characterisation of acidic heteroglycans from Tremella fuciformis Berk with cytokine stimulating activity. Carbohydr. Res. 288: 135-142.

    Google Scholar 

  • Gao Q,Killie MK,Chen H,Jiang R,Seljejid R (1997) Characterization and cytokine-stimulating activities of acidic heteroglycans from Tremella fuciformis. Planta Med. 63: 457-460.

    Google Scholar 

  • Golubev WI (1991) Capsules. In: Rose AH,Harrison JS, eds. The Yeasts-Yeast Organelles. London, San Diego: Academic Press, pp. 174-197.

    Google Scholar 

  • Jeanes A,Pittsley JE,Watson PR (1964) Extracellular polysaccharide produced from glucose by Cryptococcus laurentii var. flavescens NRRL Y-1401: chemical and physical characterization. J. Appl. Polym. Sci. 8: 2775-2787.

    Google Scholar 

  • Kakuta M,Sone Y,Umeda T,Misaki A (1979) Comparative structural studies on acidic heteropolysaccharides isolated from 'shirokikurage', fruit body of Tremella fuciformis Berk, and the growing culture of its yeast-like cells. Agricult. Biol. Chem. 43: 1659-1668.

    Google Scholar 

  • Kiho T,Kobayashi T,Morimoto H,Usui S,Ukai S,Hirano K,Aizawa K,Inakuma T (2000a) Structural features of an antidiabetic polysaccharide (TAP) from Tremella aurantia. Chem. Pharm. Bull. 48: 1793-1795.

    Google Scholar 

  • Kiho T,Morimoto H,Kobayashi T,Usui S,Ukai S,Aizawa K,Inakuma T (2000b) Effect of a polysaccharide (TAP) from the fruiting bodies of Tremella aurantia on glucose metabolism in mouse liver. Biosci. Biotechnol. Biochem. 64: 417-419.

    Google Scholar 

  • Kiho T,Morimoto H,Sakushima M,Usui S,Ukai S (1995) Polysaccharides in fungi. XXXV. Anti-diabetic activity of an acidic polysaccharide from the fruiting bodies of Tremella aurantia. Biol. Pharm. Bull. 18: 1627-1629.

    Google Scholar 

  • Kiho T,Morimoto H,Usui S,Ukai S (1996) Antidiabetic activity of an acidic polysaccharide from the fruiting bodies of Tremella aurantia. In: Yalpani M, ed. Biomedical Functions and Biotechnology of Natural and Artificial Polymers. Shrewsbury, US: ATL Press, pp. 243-249.

    Google Scholar 

  • Kiho T,Tsujimura Y,Sakushima M,Usui S,Ukai S (1994) Polysaccharides in fungi. XXXIII. Hypoglycemic activity of an acidic polysaccharide (AC) from Tremella fuciformis. Yakugaku Zasshi 114: 308-315.

    Google Scholar 

  • Ma L,Lin ZB (1992) Effect of Tremella polysaccharide on IL-2 production by mouse splenocytes. Yao Hsueh Hsueh Pao 27: 1-4.

    Google Scholar 

  • Margaritis A,Pace GW (1985) Microbial polysaccharides. In: Blanch HW,Drew S,Wang DIC, eds. Comprehensive Biotechnology, Vol. 3. Oxford, UK: Pergamon Press, pp. 1005-1044.

    Google Scholar 

  • Shen R,Zhang D,Wang Y-A (1993) Tremella polysaccharide drink and its making method. Chinese Patent CN1069866.

  • Slodki ME (1966) Hydrolysis products from an extracellular Tremella polysaccharide. Can. J. Microbiol. 12: 495-499.

    Google Scholar 

  • Slodki ME,Cadmus MC (1978) Production of microbial polysaccharides. Adv. Appl. Microbiol. 23: 19-54.

    Google Scholar 

  • Slodki ME,Wickerham LJ,Bandoni RJ (1966) Extracellular heteropolysaccharides from Cryptococcus and Tremella: a possible taxonomic relationship. Can. J. Microbiol. 12: 489-494.

    Google Scholar 

  • Spencer JFT,Gorin PAJ (1973) Mannose-containing polysaccharides of yeasts. Biotechnol. Bioeng. 15: 1-12.

    Google Scholar 

  • Sutherland IW (1997) Microbial exopolysaccharides-structural subtleties and their consequences. Pure Appl. Chem. 69: 1911-1917.

    Google Scholar 

  • Sutherland IW (1998) Novel and established applications of microbial polysaccharides. Trends Biotechnol. 16: 41-46.

    Google Scholar 

  • Ukai S,Hirose K,Kiho T,Hara C,Irikura T (1972) Antitumor activity on sarcoma 180 of the polysaccharides from Tremella fuciformis Berk. Chem. Pharm. Bull. 20: 2293-2294.

    Google Scholar 

  • Vandamme EJ,Bruggeman G,De Baets S,Vanhooren PT (1996) Useful polymers of microbial origin. Agro-Food-Industry Hi-Tech 7: 21-25.

    Google Scholar 

  • Vanhooren PT,De Baets S,Bruggeman G,Vandamme EJ (1998) Plastics made by bacteria or their enzymes. Biologi Italiani 1: 7-11.

    Google Scholar 

  • Wuyong W (1998) Anti-senile anti-cancer food. Chinese Patent CN1177458.

  • Xiu R-J (1996) Accelerated wound healing. U.S. Patent 5547672.

  • Xiu R-J (1997) Stimulator of vascular endothelial cells and use thereof. U.S. Patent 5616325.

  • Yui T,Ogawa K,Kakuta M,Misaki A (1995) Chain conformation of a glucuronoxylomannan isolated from fruit body of Tremella fuciformis Berk. J. Carbohydr. Chem. 14: 255-263.

    Google Scholar 

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Authors and Affiliations

  1. Laboratory of Industrial Microbiology and Biocatalysis, Department of Biochemical and Microbial Technology, Ghent University, Coupure links 653, B-9000, Gent, Belgium

    S. De Baets & E.J. Vandamme

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  1. S. De Baets
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  2. E.J. Vandamme
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Correspondence to S. De Baets.

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De Baets, S., Vandamme, E. Extracellular Tremella polysaccharides: structure, properties and applications. Biotechnology Letters 23, 1361–1366 (2001). https://doi.org/10.1023/A:1011645724220

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