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Advances in Infection Control for Clostridioides (Formerly Clostridium) difficile Infection

  • New Technologies and Advances in Infections Prevention (A Marra, Section Editor)
  • Published:
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Abstract

Purpose of review

We reviewed seminal papers and recently published articles discussing multiple aspects of infection prevention applied to Clostridioides (formerly Clostridium) difficile infection (CDI).

Recent findings

We identified hot topics including the importance of understanding the gut microbiome in CDI and its implications from an infection prevention perspective, the increasing role of antibiotic stewardship including testing stewardship in preventing and mitigating CDI, and the increasing role of clinical decision support systems to improve early diagnosis and decrease inappropriate testing.

Summary

In addition to established infection prevention interventions, CDI control will be achieved by a combination of gut microbiome manipulation, personalized medicine based on host and agent genome analysis, and a combination of antimicrobials and testing stewardship by leveraging progressively sophisticated electronic decision systems. Automated environmental decontamination systems are not routinely recommended at this time.

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References and Recommended Reading

Papers of particular interest, published recently, have been highlighted as: •• Of major importance

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  1. Department of Medicine, Division of Infectious Diseases, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, USA

    Carlos E. Figueroa Castro MD & L. Silvia Munoz-Price MD, PhD

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  1. Carlos E. Figueroa Castro MD
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  2. L. Silvia Munoz-Price MD, PhD
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Correspondence to Carlos E. Figueroa Castro MD.

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Dr. Munoz-Price had received grant funds from Cepheid.

Dr. Figueroa Castro declares that he has no conflict of interest.

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Figueroa Castro, C.E., Munoz-Price, L.S. Advances in Infection Control for Clostridioides (Formerly Clostridium) difficile Infection. Curr Treat Options Infect Dis 11, 12–22 (2019). https://doi.org/10.1007/s40506-019-0179-y

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