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Right vs Left Hepatectomy for LDLT, Safety and Regional Preference

  • Liver Transplantation (R. Batra and D. Mulligan, Section Editors)
  • Published:
Current Transplantation Reports Aims and scope Submit manuscript

Abstract

Purposeof Review

We aim to gather up-to-date information on living liver donation trends, perspective and future directions, with a particular focus on donor safety and regional preference based on type of donor hepatectomy.

Recent Findings

Outcomes after donor hepatectomy have improved. Reported literature favors that there is no difference in complication rate based on hepatectomy side. Differences on living liver donation trends with a regional discrepancy are evident. Data shows that LDLT accounts for up to 90% of LT in Eastern countries, while it only accounts for < 10% in Western countries. Future directions include the wide dissemination of minimally invasive techniques.

Summary

Donor hepatectomy is a safe and feasible procedure regardless of hepatectomy side. Donor safety should be ensured throughout a comprehensive and detailed donor evaluation, follow-up and interdisciplinary efforts. Western countries can benefit from the vast experience of Eastern countries to increase dissemination and adopt innovative techniques.

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Abbreviations

CI:

Confidence interval

LDLT:

Living donor liver transplantation

LDRH:

Laparoscopic living donor right hepatectomy

LL:

Left lobe

LLS:

Left lateral segment

LOS:

Length of hospital stay

MIT:

Minimally invasive techniques

MHV:

Middle hepatic vein

ODRH:

Open living donor right hepatectomy

RD:

Risk difference

RL:

Right lobe

RLDRH:

Robotic living donor right hepatectomy

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Acknowledgements

The authors acknowledge Andres Ramos for providing assistance with the illustrations in this manuscript.

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  1. Division of Transplant Surgery, Department of Surgery, University of Virginia Health System, 1215 Lee Street, PO Box 800709, Charlottesville, VA, 22908-0709, USA

    Paola A. Vargas & Nicolas Goldaracena

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NG participated in conception and design of the manuscript, analysis and interpretation of data, and drafting of the manuscript. Material preparation, data collection and the literature search were performed by PV. The manuscript draft and final version was written by PV and NG. Both authors read and approved the final manuscript.

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Vargas, P.A., Goldaracena, N. Right vs Left Hepatectomy for LDLT, Safety and Regional Preference. Curr Transpl Rep 9, 240–249 (2022). https://doi.org/10.1007/s40472-022-00386-x

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