Abstract
The UK is rich in discovery science, but not enough of this world-leading science is translated for health and wealth benefits. Over the past several years, strategies have been launched in both the academic and industrial sectors to improve these outcomes. However, in order to make a step change, academia and industry need to collaborate better and in new ways. This article describes the translation strategy for the Francis Crick Institute.
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References
Department for Business, Innovation & Skills. Performance of the UK research base: international comparison—2013. https://www.gov.uk/government/publications/performance-of-the-uk-research-base-international-comparison-2013. Accessed 29 Feb 2016.
House of Commons Science and Technology Select Committee. Science and Technology Committee—eighth report. Bridging the valley of death: improving the commercialisation of research. http://www.publications.parliament.uk/pa/cm201213/cmselect/cmsctech/348/34802.htm. Accessed 29 Feb 2016.
The Francis Crick Institute. Discovery without boundaries: strategy 2013. http://www.crick.ac.uk/strategy. Accessed 29 Feb 2016.
NESTA. All together now: improving cross-sector collaboration in the UK biomedical industry. http://www.nesta.org.uk/publications/all-together-now-improving-cross-sector-collaboration-uk-biomedical-industry. Accessed 29 Feb 2016.
Sharp PA. Meeting global challenges: discovery and innovation through convergence. Science. 2014;346(6216):1468–71.
Contopoulos-Ioannidis DG, Ntzani E, Ioannidis JP. Translation of highly promising basic science research into clinical applications. Am J Med. 2003;114(6):477–84.
Van der Worp HB, Howells DW, Sena ES, Porritt MJ, Rewell S, O’Collins V, Macleod MR. Can animal models of disease reliably inform human studies? PLOS Med. 2010;7:e1000245.
Mak IW, Evaniew N, Ghert M. Lost in translation: animal models and clinical trials in cancer treatment. Am J Transl Res. 2014;6:114–8.
Cook D, Brown D, Alexander R, March R, Morgan P, Satterthwaite G, Pangalos MN. Lessons learned from the fate of AstraZeneca’s drug pipeline: a five-dimensional framework. Nat Rev Drug Discov. 2014;13:419–31.
Crick F, Koch C. The problem of consciousness. Sci Am. 1992;267(3):152–9.
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David Roblin is the Chief Operating Officer and Director of Scientific Translation at the Francis Crick Institute in London. He previously practised medicine in the UK, followed by a career in the biotech and pharmaceutical industry, where he became Head of Pfizer’s R&D in Europe.
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Roblin, D. The Francis Crick Institute: Scientific Discovery Open to Translation. Pharm Med 30, 133–135 (2016). https://doi.org/10.1007/s40290-016-0143-9
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DOI: https://doi.org/10.1007/s40290-016-0143-9