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Pulmonary scedosporiosis mimicking aspergilloma in an immunocompetent host: a case report and review of the literature

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Abstract

A case of localized lung scedosporiosis is reported here that mimicked aspergilloma in an immunocompetent host. Through this case the importance of considering Scedosporium spp. in differential diagnosis of locally invasive lung infections and fungal ball is highlighted. As it is difficult to differentiate Scedosporium from Aspergillus on clinical grounds, microscopy, radiology and histopathology, this case is further emphasizing the significance of the definitive etiological characterization of Scedosporium through culture or molecular diagnostic tools. Accurate identification of Scedosporium, surgical resection and high-dose voriconazole has been associated with favorable outcome in most reported cases of scedosporiosis.

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Acknowledgments

Antifungal susceptibility testing is supported through grants from the Higher Education Commission, Pakistan, and United States Agency for international Development. We are thankful to Dr. Joveria Farooqi for proof reading of the manuscript for English language and grammar.

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Authors and Affiliations

  1. Section of Pulmonary and Critical Care Medicine, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan

    Fasih Ur Rahman & Muhammad Irfan

  2. Department of Pathology and Microbiology, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan

    Naima Fasih & Kauser Jabeen

  3. Cardio-Thoracic Surgery, Aga Khan University Hospital, Karachi, Pakistan

    Hasanat Sharif

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  1. Fasih Ur Rahman
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  2. Muhammad Irfan
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  3. Naima Fasih
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Correspondence to Naima Fasih.

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Rahman, F.U., Irfan, M., Fasih, N. et al. Pulmonary scedosporiosis mimicking aspergilloma in an immunocompetent host: a case report and review of the literature. Infection 44, 127–132 (2016). https://doi.org/10.1007/s15010-015-0840-4

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  • DOI: https://doi.org/10.1007/s15010-015-0840-4

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