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Early Nutrition and Physical Activity Interventions in Childhood Cancer Survivors

  • Obesity Prevention (A Must, Section Editor)
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Abstract

Purpose of Review

Childhood cancer survivors experience excessive weight gain early in treatment. Lifestyle interventions need to be initiated early in cancer care to prevent the early onset of obesity and cardiovascular disease (CVD). We reviewed the existing literature on early lifestyle interventions in childhood cancer survivors and consider implications for clinical care.

Recent Findings

Few lifestyle interventions focus on improving nutrition in childhood cancer survivors. A consistent effect on reducing obesity and CVD risk factors is not evident from the limited number of studies with heterogeneous intervention characteristics, although interventions with a longer duration and follow-up show more promising trends.

Summary

Future lifestyle interventions should be of a longer duration and include a nutrition component. Interventions with a longer duration and follow-up are needed to assess the timing and sustainability of the intervention effect. Lifestyle interventions introduced early in cancer care are both safe and feasible.

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Authors and Affiliations

  1. Friedman School of Nutrition Science and Policy, Tufts University, 150 Harrison Ave, Boston, MA, 02111, USA

    Fang Fang Zhang

  2. Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA

    Fang Fang Zhang

  3. Department of Pediatrics, Tufts University School of Medicine, Boston, MA, USA

    Michael J. Kelly

  4. Division of Pediatric Hematology and Oncology, The Floating Hospital for Children, Tufts Medical Center, Boston, MA, USA

    Michael J. Kelly

  5. Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA

    Aviva Must

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  1. Fang Fang Zhang
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Correspondence to Fang Fang Zhang.

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Conflict of Interest

Fang Fang Zhang, Michael J. Kelly, and Aviva Must declare they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Sources of Support

This study was supported by NIH/NCI 1R03CA199516-01 and the Tufts Collaborates Grant. The funding sources had no role in the design, conduct, or analysis of this study or the decision to submit the manuscript for publication.

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This article is part of the Topical Collection on Obesity Prevention

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Zhang, F.F., Kelly, M.J. & Must, A. Early Nutrition and Physical Activity Interventions in Childhood Cancer Survivors. Curr Obes Rep 6, 168–177 (2017). https://doi.org/10.1007/s13679-017-0260-0

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