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Allergy to Hematophagous Arthropods Bites

  • Immunology (HC Lima, Section Editor)
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Abstract

Allergies to hematophagous arthropod bites are inflammatory reactivity to arthropods salivary components. They vary in intensity and quality dependent upon the arthropod species and the individual immune response to specific proteins of the insect’s saliva. Individuals who were not previously exposed show mild localized reactions not beyond those expected by pharmacological substances present in arthropods’ saliva. Allergic reactions are immunological in their nature and the diversity derived from hypersensitivity reactions with different levels of participation of the immune system components. Some are mainly derived from a humoral immune response, and others are based predominantly on T-lymphocyte-mediated. The majority of these undesired biological answers are self-limited, and few may cause a systemic reaction. This article intends to discuss the immunological ingredients of this evolutionary interaction.

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Acknowledgments

The authors thank Tony and Blazenka Matic for their assistance and review. We regret to acknowledge the death of Richard Titus, an expert in insect bite immunology in January, 2013.

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Conflict of Interest

MA Miot declares no conflicts of interest.

HC Lima declares no conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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  1. Departamento de Dermatologia, SN, Unesp Medical School, Campus Universitário de Rubião Jr, Botucatu, SP, Brazil, 1861800

    Hélio Amante Miot

  2. Division of Dermatology, Department of Medicine - Michael G. DeGroote School of Medicine, McMaster University, 1280 Main Street, West Hamilton, Ontario, L8S4L8, Canada

    Hermenio C. Lima

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Miot, H.A., Lima, H.C. Allergy to Hematophagous Arthropods Bites. Curr Derm Rep 3, 6–12 (2014). https://doi.org/10.1007/s13671-013-0065-7

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