Abstract
Collision-induced dissociation (CID) experiments were performed on atmospheric ion adducts [M + R]– formed between various types of organic compounds M and atmospheric negative ions R- [such as O2 –, HCO3 –, COO–(COOH), NO2 –, NO3 –, and NO3 –(HNO3)] in negative-ion mode atmospheric pressure corona discharge ionization (APCDI) mass spectrometry. All of the [M + R]– adducts were fragmented to form deprotonated analytes [M – H]– and/or atmospheric ions R–, whose intensities in the CID spectra were dependent on the proton affinities of the [M – H]– and R– fragments. Precursor ions [M + R]– for which R- have higher proton affinities than [M – H]– formed [M – H]– as the dominant product. Furthermore, the CID of the adducts with HCO3 – and NO3 -(HNO3) led to other product ions such as [M + HO]– and NO3 –, respectively. The fragmentation behavior of [M + R]– for each R– observed was independent of analyte type (e.g., whether the analyte was aliphatic or aromatic, or possessed certain functional groups).
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The authors acknowledge support for this work by a Grant-in-Aids for Scientific Research (C) (23550101 and 24619005) from the Ministry of Education, Culture, Sports, and Technology in Japan, and a Grant-in-Aid for Research Activity Start-Up of the Japan Society for the Promotion of Science (JSPS) (22810025).
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Sekimoto, K., Takayama, M. Collision-Induced Dissociation Analysis of Negative Atmospheric Ion Adducts in Atmospheric Pressure Corona Discharge Ionization Mass Spectrometry. J. Am. Soc. Mass Spectrom. 24, 780–788 (2013). https://doi.org/10.1007/s13361-013-0576-2
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DOI: https://doi.org/10.1007/s13361-013-0576-2